Macrene Actives - High Performance Lip Filler - Clear 5ml

Formulated by Dr. Macrene Alexiades, MD, PhD · Dual Board-Certified Dermatologist & Research Scientist

The original. The only MD PhD-formulated lip filler clinically designed to replace the needle — not just plump the surface.

Dr. Alexiades spent decades injecting lips. She knows better than anyone what injectable filler does, how it does it, and what it cannot do. This formula was built from that clinical knowledge — not inspired by it, not approximating it, but engineered from the inside out to replicate the volumizing, smoothing, and structural mechanisms of injectable lip filler through a 20+ active system that works deeper, lasts longer, and improves with every application.

Wear it daily. The results compound over time. This is the lip treatment you use for decades so you do not need injections.